Selected Collagen Publications:
Roth, J., Hoop, C.L., Williams, J.K., Nanda, V., Baum, J. "Real-time single-molecule observation of incipient collagen fibrillogenesis and remodeling." Proc. Natl. Acad. Sci. (2024) doi:10.1073/pnas.2401133121
Roth, J., C.L. Hoop, J.K. Williams, R. Hayes, and J. Baum. “Probing the Effect of Glycosaminoglycan Depletion on Integrin Interactions with Collagen I Fibrils in the Native Extracellular Matrix Environment.” Protein Science. 32:e4508 (2023). doi:10.1002/pro.4508
Hoop, C.L., J. Zhu, S. Bhattacharya, C.A. Tobita, S.E. Radford, and J. Baum. "Collagen I Weakly Interacts with the β-sheets of β2-Microglobulin and Enhances Conformational Exchange to Induce Amyloid Formation." J. Am. Chem. Soc. 142:1321-1331 (2020). doi: 10.1021/jacs.9b10421
Selected α-Synuclein Publications:
Khare, S.D., Chinchilla, P., Baum, J. "Multifaceted interactions mediated by intrinsically disordered regions play key roles in alpha synuclein aggregation." Curr. Opin. Struct. Biol. (2023). doi:10.1016/j.sbi.2023.102579
Atieh, T.B., J. Roth, X. Yang, C.L. Hoop, and J. Baum. "DJ-1 Acts as a Scavenger of alpha-Synuclein Oligomers and Restores Monomeric Glycated alpha-Synuclein." Biomolecules (2021). doi:10.3390/biom11101466
Stoeber, J., J.K. Williams, P.V. Moghe, and J. Baum. "Tannic Acid Inhibits a-Synuclein Amyloid Fibril Formation via Binding to the Monomer N-terminal Domain." bioRxiv. (2021). doi:10.1101/2021.05.26.445860
Yang, X., B. Wang, C.L. Hoop, J.K. Williams, and J. Baum. "NMR Unveils an N-terminal Interaction Interface on Acetylated-α-synuclein Monomers for Recruitment to Fibrils." Proc. Natl. Acad. Sci. USA. (2021). doi:10.1073/pnas.2017452118
Zhao, N., X. Yang, H.R. Calvelli, Y. Cao, N.L. Francis, R.A. Chmielowski, L.B. Joseph, Z.P. Pang, K.E. Uhrich, J. Baum, and P.V. Moghe. "Antioxidant Nanoparticles for Concerted Inhibition of α-Synuclein Fibrillization, and Attenuation of Microglial Intracellular Aggregation and Activation." Frontiers in Bioengineering and Biotechnology. 8: 112 (2020). doi:10.3389/fbioe.2020.00112
Zhang, J., E.S. Park, H.-J. Park, R. Yan, M. Grudniewska, X. Zhang, S. Oh, X. Yang, J. Baum, and M.M. Mouradian. "Apoptosis Signal Regulating Kinase 1 Deletion Mitigates the α-Synuclein Pre-formed Fibril Propagation Model in Mice." Neurobiology of Aging. 85: 49–57 (2020). doi:10.1016/j.neurobiolaging.2019.09.012
Selected COVID-19 Publications:
Williams J.K., B. Wang, A. Sam, C.L. Hoop, D.A. Case and J. Baum. "Molecular Dynamics Analysis of a Flexible Loop at the Binding Interface of the SARS-CoV-2 Spike Protein Receptor-Binding Domain." Proteins: Structure, Function, and Bioinformatics (2021). doi:10.1002/prot.26208
